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l that we may be about to enter a shift in eras. War, sanctions, disrupted supply chains, and blocs have all become part of our everyday vocabulary., We should recognize that the Asia-Pacific region sits in the middle of many global macro fault lines. , Three Macro Trends To understand the key forces acting on the Asia-Pacific region today, we should recognize that it sits in the middle of many global macro fault lines, with three particularly notable trends emerging.

reatment, and trust that our doctors have all the information they need to treat us as unique individuals. That is the promise of genomic medicine., An estimated 65 million human genomes are expected to be sequenced by 2025. , Take, for example, a critically ill baby in intensive care where doctors are struggling to find a diagnosis.

nd disruption, the recent periods of turbulence and the pandemic made this necessity abundantly clear., To further succeed, one needs to be agile and able to move at multiple speeds across three horizons. , Optimizing for Today: Less Is More

on, modern slavery, inequality, climate disasters, pandemics., Hope and conviction may be the only strategy. Collective action and innovation will be our currency. , When speaking with business leaders, I’ve often heard (and sometimes repeated) that “hope isn’t a strategy.” This is, of course, meant to be a warning against sloppy planning.

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s of remission and relapse.

cting the same old things with the same old people.  , "A meaningful life is about the willingness to start conversations around the unimaginable and then to work to make the unimaginable happen." , This year, presidential elections were held in Afghanistan, something I could not have imagined 20 years ago. That transformation came about through the commitment and willingness of many voices to work together to create change.

BC–65 AD)  , "Having a fulfilling life as a clinician is not just about the science of medicine but, equally importantly, is about the art of medicine, too." , Having a fulfilling life as a clinician is not solely about the science of medicine but, equally importantly, about the art of medicine, also.

n the Gulf of Mexico, and the San Jose copper mine collapse that trapped 33 Chilean miners underground., "On my current expedition to cure paralysis, I am finding and working with incredible pioneers all around the world who too often work in isolation." , Today, in this work, I feel more aligned with the Polar explorers than I ever did racing to the South Pole. Like those early geographic expeditions into the unknown, there was no individual hero. The true story was always one of collaboration.

, "I am a firm believer that if we want to exact change on a macro scale, we all have to take personal responsibility for making changes on a smaller scale." , I am a firm believer that if we want to exact change on a macro scale, we all have to take personal responsibility for making changes on a smaller scale.

uccess, the perception of a meaningful life has become one where our own ambitions are achieved. , "To build a meaningful life, we should aspire to become meaningful to others." , To develop a truly meaningful life, we must first shed the burden of other people’s perceptions of what it is to be meaningful and understand that it is about others more than it is about ourselves. 

any of us give real, serious thought to the meaning of life—especially when we are younger, healthy, feeling immortal?" , Who wouldn’t focus 1,000 percent on living after receiving a letter like the one above? But how many of us give real, serious thought to the meaning of life—especially when we are younger, healthy, feeling immortal?