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report
Strengthening the Biomedical Innovation Ecosystem: A Scorecard for System Assessment
As patients, we often evaluate our interactions within the "system" of biomedical innovation with a
simple question: "Did it work for me?" This evaluation considers many issues, including whether the best treatments are accessible and available, how the
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Cell and Gene Therapies: Looking Ahead to 2022
Cell and gene therapies are a new category of medicines transforming how we treat and potentially c
ure disease. Both cell and gene therapies seek to modify genetic material to fight disease.
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COVID-19 Silver Linings for Biomedical Innovation: Implementation Roadmap
While the response to the COVID-19 pandemic has exposed many of the fault lines in the biomedical i
nnovation ecosystem that have slowed progress for decades, we have also shown ourselves capable of innovating in ways we perhaps did not think possible.
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Neurotechnology: A Giving Smarter Guide
When most people think about advances in medicine, drug development is the first thing that comes t
o mind. However, technology and devices are proving to be valuable options for treating intractable illnesses.
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The Promise of Multi-Cancer Early Detection Technologies in Encouraging Research and Development
New blood-based technologies, known as multi-cancer early detection (MCED) tests, are entering 
;the market and can identify multiple cancers early and simultaneously.
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Sarcoidosis: A Giving Smarter Guide
The Milken Institute Center for Strategic Philanthropy and the Ann Theodore Foundation have release
d a new request for proposals (RFP) focused on understanding the underlying biology of sarcoidosis.
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Solving the Philanthropist's Dilemma
Philanthropic capital has played and will continue to play a critical role as we rebuild after the
pandemic.
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Moonshots for Youth Mental Health and Well-Being: Exploration of Big Bets and Bold Goals
Good mental health is critical to overall health and well-being, but a cycle of almost endless stre
ssors, stigma, and systemic barriers to accessing quality care have brought America’s collective mental health to a breaking point.
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Bladder Cancer - A Giving Smarter Guide
More than 500,000 people in the US suffer from bladder cancer. At the time of this report, it
was the fifth most common cancer in the US. It is also the most expensive cancer to treat and frequently reoccurs.
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Alzheimer's Disease - A Giving Smarter Guide
Alzheimer’s disease is increasingly in the spotlight after a number of high-profile clinical trial
failures—an alarming trend as an estimated 5.5 million adult Americans live with this disease, which disproportionally affects the aged population.
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Kidney Failure - A Giving Smarter Guide
This Giving Smarter Guide is the culmination of a year-long effort to identify strategic philanthro
pic opportunities that can move the needle on unmet needs specific to kidney failure research and treatment. Kidney failure is an irreversible diseas
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Alzheimer's Disease: A Giving Smarter Guide to Accelerate Development of New Therapies
The need is staggering. Alzheimer's disease is the sixth leading cause of death in the United State
s and currently, more than 5.5 million Americans are living with this disease for which there is yet no cure yet.
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